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01.

medRxiv (Medicine) 2026-06-18 DOI: HASH:42c939cd9d60e7324856eac14871b703

Expert in Ultrasound Skills: Feasibility of an IMU-video platform to describe technical profiles during focused cardiac ultrasound. Pilot study

作者:

morales↗f. r↗Gonzalez↗S. R↗Osses↗M. F. S↗Hernandez↗B. L↗Ramirez↗D. A↗

Background: Focused cardiac ultrasound (FoCUS) is operator dependent and requires coordinated probe manipulation, image interpretation and iterative visual feedback. Existing assessment approaches often emphasize final image quality or expert rating. We developed Expert in Ultrasound Skills (EXUS) , a platform that synchronizes transducer-mounted inertial measurement unit (IMU) data with ultrasound video, and evaluated its technical feasibility during FoCUS acquisition. Methods: This observational pilot study included 6 operators performing two repetitions of a four-view FoCUS protocol, yielding 12 analytical sessions and 48 planned acquisitions. Feasibility was defined by acquisition completion, video availability, start/stop events, fused IMU-video windows, temporal coverage, complete human label entries and IMU integrity. A 100-image Likert rating task was used to summarize pairwise inter-rater agreement for still-frame image quality assessment. Results: All 48 planned acquisitions were completed with video, start/stop events, fused windows and complete human label entries. Temporal coverage was at least 90% in 47/48 acquisitions. IMU integrity endpoints exceeded the 80% threshold: 43/48 acquisitions had no extreme IMU-derived artifact, 43/48 had no active-segment IMU restart and 44/48 had no complete motion flatline. Mean pairwise exact agreement for the Likert task was 38.9%, with mean quadratic-weighted Cohen's kappa of 0.564. Post hoc profiles varied across duration, visual quality, mechanical load and motor efficiency. Conclusions: EXUS was technically feasible for synchronized IMU-video capture during FoCUS. The pilot supports multimodal acquisition data as a way to describe technical profiles and generate formative feedback hypotheses, but the post hoc indices are not validated competency measures. Keywords: focused cardiac ultrasound; point-of-care ultrasound; inertial measurement unit; medical education; deliberate practice

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02.

arXiv (CS.AI) 2026-06-12 DOI: arXiv:2606.13179

Modern analog computing for solving differential and matrix equations

作者:

Zhong Sun↗Piergiulio Mannocci↗Manuel Le Gallo↗Abu Sebastian↗

arXiv:2606.13179v1 Announce Type: cross Abstract: In recent years, driven by the computational demands of data-intensive applications such as artificial intelligence and scientific computing, analog computing has gained renewed interest. Given the diversity of computational tasks and recent advancements in analog CMOS circuits and resistive memory technologies, we refer to the evolving landscape as modern analog computing. In this context, we identify three core computational primitives: solving differential equations, solving matrix equations, and performing matrix-vector multiplications, and we explore the connections among them. We also examine various hardware implementations of these analog computing operators, including those built with discrete components, integrated circuits, and resistive memory devices. Among these, resistive memory arrays emerge as particularly promising due to their implementation efficiency. The paper then surveys recent progress in leveraging modern analog computing to solve differential and matrix equations using both advanced analog CMOS circuits and resistive memory arrays. Finally, we discuss the applications of these circuits, the precision and scalability issues and their potential solutions, the relationship with in-memory computing, and the unique computational complexity of analog computing. This paper provides a unified perspective on analog computing, highlighting its strengths, current developments, and challenges, and positioning it as a pivotal enabler of next-generation computational frontiers.

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03.

bioRxiv (Bioinfo) 2026-06-18 DOI: HASH:abc719c3f21fb641a7199808d2939495

Metrics for Evaluating Biological AI Model Predictive Accuracy at the Data-Substrate Level

作者:

Ewing↗M. A↗

Reports in the biological literature disagree on whether a given model can predict a biological outcome from a given data sample — one study finding a model capable, another, on the same kind of data, finding it is not. This is particularly a challenge in relation to LLMs–where the models are large and opaque, with weights and training data inaccessible.textbf{ }Such disagreements cannot be settled by directly inspecting the model. To address this challenge, we considertextbf{ }an alternative approach: assessing whether the data sample is adequate to support the prediction asserted. For a given dataset, its substrate — the underlying structure of the data — determines what any model can recover, independent of architecture or capacity. At the same time, predicting the present state of a biological process and predicting the direction of its future change are different tasks; the second is supportable among AI models only where the data encode direction as determinable from the state — a property we call encoding — and is unsupportable where the same observed state precedes change in opposite directions — a property we call non-identifiability, in the informational rather than the statistical sense. We introduce two generic metrics, Predictive Blindness Risk (PBR) and Prediction Indeterminacy Measure (PIM), that evaluate a data substrate for predictive accuracy directly — without access to model weights, architecture, or training data — and locate the regions of a data substrate where a predictive claim can be supported and where it cannot. Using human biological subjects, we employ the Yale Brain Metastases Longitudinal Data (1,430 human subjects; 11,892 MRI studies; four sequences) and show that direction of change was non-identifiable across regions encompassing the majority of transitions; a nonlinear AI model gained essentially nothing over majority-direction prediction there while recovering direction near-perfectly where the state encoded it; and model accuracy tracked data-substrate resolvability continuously (Spearman {rho} = -0.95 to -1.00). The metrics adjudicate, before any model is trusted and from the data alone, where claims of predictive accuracy — of state, or of the law of change — can be supported.

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04.

arXiv (CS.LG) 2026-06-25 DOI: arXiv:2606.24955

Towards Continuous Power Forecasting: Practical Continual Learning for Real-World Energy Systems in Nonstationary Time Series

作者:

Yujiang He↗Frederic Uhrweiller↗Bernhard Sick↗

arXiv:2606.24955v1 Announce Type: new Abstract: Power forecasting models deployed in real-world energy markets must operate under nonstationary conditions, where data distributions continually evolve due to weather variability, infrastructure upgrades, and changing consumption behaviors. In practice, these models face strict operational constraints: historical data may be limited or unavailable for repeated retraining, and uninterrupted long-term service is often required. This paper addresses these challenges by proposing the paradigm of Continuous Power Forecasting, which views power forecasting as a continual learning problem rather than a static offline task. Based on an adaptive continual learning framework for regression, we systematically investigate the practical effectiveness of six representative continual learning approaches from three methodological categories. These approaches are evaluated under different realistic assumptions regarding data accessibility and update policies. Experimental validation on real-world power datasets demonstrates that continual learning enables forecasting models to self-adapt to distributional drift, accumulate knowledge over time, and mitigate catastrophic forgetting without relying on large-scale historical data storage. Beyond performance gains, our study provides practical insights into the stability and adaptation behaviors of different continual learning approaches under realistic operational constraints. Overall, this work illustrates how continual learning can be pragmatically integrated into industrial power forecasting pipelines, offering a scalable and sustainable solution for long-term deployment in dynamic environments.

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05.

arXiv (CS.AI) 2026-06-12 DOI: arXiv:2606.13192

Reasoning for Mobile User Experience with Multimodal LLMs: Task, Benchmark, and Approach

作者:

Ruichao Mao↗Zhou Fang↗Teng Guo↗Hao Yang↗Yaping Li↗Shaohua Peng↗Maji Huang↗Xiaoyu Lin↗Shuoyang Liu↗Xuepeng Li↗Yuyu Zhang↗Hai Rao↗…

arXiv:2606.13192v1 Announce Type: new Abstract: User experience (UX) centered on usability, perceived consistency, and functional clarity is fundamental to real-world user interfaces (UI). The application of multimodal large language models (MLLMs) in the field of user interfaces is evolving rapidly, such as visual element grounding, graphical user interface (GUI) agents, and design-to-code generation. However, research efforts on evaluating UX based on UI screenshots are still immature. To address this, we propose UXBench, a novel multimodal benchmark consisting of 2,000 VQA data samples designed to assess MLLMs' ability to perform UI-based reasoning. UXBench includes 8 tasks based on real-world UI screenshots that require fine-grained diagnosis of UX issues across layout relationships, visual hierarchy, and content consistency. Our extensive evaluation of mainstream MLLMs shows that they remain fundamentally limited in their capacity for UI-based reasoning. The results underscore the need for further advancements in this area. To bridge this gap, we propose UI-UX, an MLLM based on Qwen3-VL-4B-Thinking foundation model and enhanced via reinforcement learning with two key innovations: a reward routing mechanism that dynamically balances perceptual understanding and logical reasoning during inference, and an asymmetric transition reward that suppresses redundant or insufficient reasoning steps. Experiments demonstrate that UI-UX achieves state-of-the-art (SOTA) performance on UXBench, attaining an accuracy of 0.7963 – surpassing Claude-4.5-Sonnet's 0.6550 – while exhibiting strong generalization across diverse UI tasks and maintaining low inference latency.

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06.

arXiv (quant-ph) 2026-06-16 DOI: arXiv:2606.15190

Lattice surgery for near-term experimental logical qubit entanglement creation in planar architectures

作者:

Lukas B\"odeker↗\'Aron M\'arton↗Luis Colmenarez↗Ilya Besedin↗Andreas Wallraff↗Markus M\"uller↗

arXiv:2606.15190v1 Announce Type: new Abstract: In the era of early fault-tolerant quantum computing, basic demonstrations of entanglement operations between a few logical qubits are at the frontier of recent developments in quantum computing. In this work, we describe in detail, at both the logical and physical qubit levels, a logical teleportation protocol between two surface code logical qubits based on lattice surgery. We address several aspects of the teleportation protocol pertinent to superconducting qubit architectures. We explore the modularity constraints in the number and location of stabilizer readouts and compare variants of the teleportation protocol in this regard. Additionally, we investigate potential performance improvements related to in-sequence decision logic and the optimal size of the interface region between two surface code patches on a superconducting chip. Based on our simulations, we show possible near-term improvements in lattice surgery protocols that facilitate fault-tolerant quantum computing in superconducting circuit architectures.

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07.

bioRxiv (Bioinfo) 2026-06-10 DOI: HASH:14fabbef358acb248edf790c2dfcd718

GEOAgent: An AI-driven Autonomous Framework for Intelligent GEO Data Retrieval and Standardized Preprocessing

作者:

Zhao↗Cai↗Chen↗

Datasets in the Gene Expression Omnibus (GEO) remain difficult to reuse at scale because sample annotations are heterogeneous and raw sequencing data require assay-specific preprocessing. We present GEOAgent, an AI-driven autonomous framework designed for intelligent dataset retrieval and standardized preprocessing by coupling autonomous semantic governance with an automated Nextflow pipeline named bioStream. Metadata from 181,760 sequencing series and 84,756 associated PubMed records were organized in a relational database and semantic index to support natural-language dataset retrieval. The framework automatically determines assay modalities, resolves experimental design pairings, and standardizes sample naming to minimize manual curation overhead. Based on these parsed attributes, the framework generates deployment-ready manifests to automatically execute containerized workflows across bulk and single-cell omics modalities. In expert-curated benchmarks, the workflow achieved 96% retrieval precision alongside 100% accuracy in assay classification and sample relationship resolution. The web platform is publicly accessible, while the source code and associated databases are openly available via GitHub and Zenodo.

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08.

arXiv (CS.CV) 2026-06-16 DOI: arXiv:2606.16794

LLM-Based Visual Explanation Evaluation Framework for Assessing the Explainability of Facial Skin Disease Classification Models

作者:

Gyuyeon Na↗

This study proposes a domain-specific LLM-based Visual Explanation Evaluation Framework for assessing Grad-CAM explanations in facial skin disease diagnosis models. While previous studies have primarily focused on improving classification performance through data augmentation techniques, relatively few studies have systematically examined whether model explanations are grounded in clinically relevant lesion regions. In this study, geometric augmentation, color-based augmentation, and mixed augmentation strategies were applied to facial skin disease classification models based on EfficientNet-B0, MobileNetV3, and ResNet18. Grad-CAM was employed to generate visual explanations representing the models' decision-making processes. Furthermore, an LLM-as-a-Judge evaluation framework was designed using GPT-5.5, Gemini 3.5 Flash, and Claude Sonnet 4.6 to assess Grad-CAM explanations from the perspectives of lesion localization and explanation trustworthiness. To improve evaluation consistency and clinical grounding, a progressive prompt engineering strategy was introduced, incorporating evaluation rubrics, clinical knowledge, penalty rules, and structured output formats.

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09.

arXiv (CS.CL) 2026-06-18 DOI: arXiv:2606.18797

Beyond Scalar Scores: Exploring LLM-based Metrics for Clinical Significance Evaluation in Radiology Reports

作者:

Qingyu Lu↗Ruochen Li↗Liang Ding↗Yufei Xia↗Youxiang Zhu↗Dacheng Tao↗

Reliable evaluation of generated radiology reports requires strict clinical accuracy, as omitted critical findings or mischaracterized radiographic observations can directly affect patient care. Existing metrics obscure this requirement by reducing report quality to a medically ungrounded scalar. Although Large Language Models (LLMs) possess rich medical knowledge, they likewise struggle to draw a reliable boundary between clinically significant errors and harmless variation. We study this boundary using ReEvalMed benchmark as testbed and evaluate metric-level clinical significance from detecting true clinical errors ("Discrimination") and tolerating insignificant variations ("Robustness"). Across 8 LLM evaluators under one-pass and two-pass settings, we identify a widespread discrimination bias: models effectively detect errors but also over-penalize harmless rephrasings. To mitigate this, we synthesize 4k report pairs and train lightweight interpretable metrics on Qwen3-8B and MedGemma-4B. Our trained metric sharpens the clinical significance boundary, surpassing 32B-scale medical LLMs and remaining competitive with proprietary models. Crucially, the more costly two-pass setting fails to consistently improve overall performance and mainly trades discrimination for robustness. These findings suggest one-pass trained metrics as the practical choice for cost-sensitive deployment, with two-pass inference reserved for settings where D-R balance is critical. We will release the dataset and metric.

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10.

arXiv (math.PR) 2026-06-16 DOI: arXiv:2606.16005

An Algebraic Matrix Spencer Theorem

作者:

Emrullah Akbas↗Suvrit Sra↗

arXiv:2606.16005v1 Announce Type: new Abstract: We develop an algebraic approach to matrix discrepancy based on the representation theory of finite-dimensional C$^*$-algebras. As an application, we resolve a substantial structured special case of the Matrix Spencer conjecture. In particular, we show that for every family of contractions $A_1,\ldots,A_n$ that are contained in a finite-dimensional $C^*$-algebra $\mathcal A$ with $dim_{\mathbb C} (\mathcal A) \lesssim n$, there exists signs $x\in\{\pm1\}^n$ such that $\|\sum_{i=1}^n x_i A_i\| \le O(\sqrt n)$. As a noteworthy special case, our main result also resolves the Group Spencer conjecture of (Bandeira'24). We furthermore prove that Matrix Spencer continues to hold for low-rank perturbations of matrix families coming from an $C^*$-algebra of small dimension.

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11.

arXiv (CS.AI) 2026-06-16 DOI: arXiv:2604.02343

Haiku to Opus in Just 10 bits: LLMs Unlock Large Compression Gains

作者:

Roy Rinberg↗Annabelle Michael Carrell↗Simon Henniger↗Nicholas Carlini↗Keri Warr↗

arXiv:2604.02343v2 Announce Type: replace-cross Abstract: We study the compression of LLM-generated text across lossless and lossy regimes, characterizing a compression-compute frontier where more compression is possible at the cost of more compute. For lossless compression, domain-adapted LoRA adapters can improve LLM-based arithmetic coding by 2x over compression with the base LLM alone. For lossy compression, prompting a model for a succinct rewrite then applying arithmetic coding can achieve compression ratios of approximately 0.03, a 2x improvement over compressing the original response. We further introduce Question-Asking compression (QA), an interactive lossy protocol inspired by the game 'Twenty Questions'. A small model iteratively refines its response by asking yes/no questions to a stronger model, transferring exactly one bit per answer. On 8 benchmarks spanning math, science, and code, 10 binary questions recover 23% to 72% of the capability gap between a small and large model on standard benchmarks and 7% to 38% on harder benchmarks, achieving compression ratios of 0.0006 to 0.004. This is over 100x smaller than prior LLM-based compression (Deletang et al., 2024), suggesting that interactive protocols can transfer knowledge far more efficiently than transmitting full responses.

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12.

arXiv (quant-ph) 2026-06-11 DOI: arXiv:2405.00215

Quantum thermodynamics of the Caldeira-Leggett model with non-equilibrium Gaussian reservoirs

作者:

Vasco Cavina↗Massimiliano Esposito↗

arXiv:2405.00215v5 Announce Type: replace Abstract: We introduce a non-equilibrium version of the Caldeira-Leggett model in which a quantum particle is strongly coupled to a set of engineered reservoirs. The reservoirs are composed by collections of squeezed and displaced thermal modes, in contrast to the standard case in which the modes are assumed to be at equilibrium. The model proves to be very versatile. Strongly displaced/squeezed reservoirs can be used to generate an effective time dependence in the system Hamiltonian and can be identified as sources of pure work. In the case of squeezing, the time dependence is stochastic and breaks the fluctuation-dissipation relation, this can be reconciled with the second law of thermodynamics by correctly accounting for the energy used to generate the initial non-equilibrium conditions. To go beyond the average description and compute the full heat statistics, we treat squeezing and displacement as generalized Hamiltonians on a modified Keldysh contour. As an application of this technique, we show the quantum-classical correspondence between the heat statistics in the non-equilibrium Caldeira-Leggett model and the statistics of a classical Langevin particle under the action of squeezed and displaced colored noises. Finally, we discuss thermodynamic symmetries of the heat generating function, proving a fluctuation theorem for the energy balance and showing that the conservation of energy at the trajectory level emerges in the classical limit.

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13.

arXiv (CS.AI) 2026-06-11 DOI: arXiv:2606.12387

TAHOE: Text-to-SQL with Automated Hint Optimization from Experience

作者:

Zhiyi Chen↗Jie Song↗Peng Li↗

arXiv:2606.12387v1 Announce Type: cross Abstract: Large Language Models (LLMs) have democratized database access through Text-to-SQL, but moving from prototypes to production remains difficult. Real deployments must handle strict SQL dialects, massive schemas, and evolving user preferences, while supervised fine-tuning is costly and rigid and agentic test-time scaling is expensive. We present Tahoe, a system that treats prompt optimization as a dynamic data management problem. Tahoe uses an error-driven hint learning pipeline across Development and Deployment to consolidate debugging traces into a structured Hint Bank. Compiler feedback is distilled into reusable Syntax Hints for dialect-specific rules, while execution and user feedback are converted into Semantic Hints for schema- and user-specific logic. Tahoe further introduces a Strategy Layer that models conflicting user intents as competing strategies under shared natural-language triggers, with recency signals and post-learning attribution statistics that summarize empirical success, harm, inertness, and support. At inference time, Tahoe retrieves relevant hints and guides the LLM through Logic Planning followed by SQL Synthesis. We implement and evaluate the development-phase workflow, leaving deployment-time human-feedback updates for future work. On Spider 2.0-Snow, Tahoe substantially improves Text-to-SQL without updating model parameters. On 113 supervised Spider 2.0-Snow-0212 examples using GPT-5.5, Tahoe raises pass rate from 61.95 percent to 79.42 percent and pass-at-4 from 72.57 percent to 87.61 percent, achieves 100 percent Snowflake syntax pass rate, and reduces average compiler-feedback critic rounds from 2.79 to 0.12 per sampled candidate. The same Hint Bank also transfers to weaker backbones, including a 19.7 percentage-point pass-rate gain on Doubao-2.0-lite.

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14.

arXiv (CS.AI) 2026-06-25 DOI: arXiv:2606.21333

Ramanujan Graph Rewiring with Non Negative Resistance Curvature

作者:

Hugo Attali↗Rachid El Jouhri↗

arXiv:2606.21333v2 Announce Type: replace-cross Abstract: Graph Neural Networks (GNNs) have emerged as a powerful paradigm for learning on graph-structured data by iteratively propagating and aggregating information across edges. However, conventional message passing schemes often suffer from over-squashing, whereby exponentially large neighborhoods are compressed into fixed-dimensional embeddings, impeding effective long-range dependency learning. In this work, we introduce Ramanujan Propagation, a graph rewiring strategy that leverages Ramanujan graphs to alleviate topological bottlenecks in GNNs. We first establish that suitably chosen Ramanujan graphs guarantee non-negative resistance curvature, which mitigates over-squashing and facilitates efficient information flow. We then propose an algorithmic framework to construct a Ramanujan rewired graph that preserves the local connectivity of the original graph. Our experiments demonstrate that our method outperforms nine state-of-the-art rewiring techniques. These results establish Ramanujan graphs as a rigorous structural prior for scalable, topology-aware message passing in GNNs.

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15.

arXiv (CS.CL) 2026-06-24 DOI: arXiv:2606.23948

Layer-wise Probing of wav2vec 2.0 and Whisper for Consonant Cluster Reduction in African American English

作者:

Hamid Mojarad↗Kevin Tang↗

Self-supervised and supervised speech models are increasingly used to investigate which linguistic information their internal representations encode, and at what level of abstraction they encode it. One underexplored phenomenon is consonant cluster reduction (CCR) in African American English (AAE), a widespread phonological process and a source of automatic speech recognition (ASR) disparity. To examine how CCR is represented, we conduct speaker-independent layer-wise probing of wav2vec2-base and Whisper-small using two tasks: segmental reduction detection and segmental restoration of underlying cluster identity. Both models distinguish reduced and canonical forms with high accuracy. Crucially, reduced segments retain cues to their underlying stops, indicating that CCR is encoded as structured gradient phonological variation rather than simple segmental deletion. These results demonstrate structured phonological encoding of AAE CCR patterns in modern speech models.

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16.

arXiv (CS.CL) 2026-06-17 DOI: arXiv:2505.19937

ALAS: An Automatic Latent Alignment Score for Audio Language Models

作者:

Pooneh Mousavi↗Yingzhi Wang↗Mirco Ravanelli↗Cem Subakan↗

Large Language Models (LLMs) are extended into Speech-LLMs, and the quality of the audio–text alignment they learn affects most downstream Spoken Language Understanding (SLU) behavior. Yet despite a growth of fusion strategies, there is no standard way to measure how well a Speech-LLM internally binds audio frames to text tokens. We introduce ALAS (Automatic Latent Alignment Score), a model and task-agnostic metric that probes the LLM's per-layer hidden states, scoring the cross-modal cosine similarity between audio and text representations against a Whisper-derived reference. ALAS needs only a frozen forward pass and an off-the-shelf ASR reference, with no training or fitted classifier, and is calibrated to an interpretable uniform baseline comparable across tasks. Applying ALAS to four open-source Speech-LLMs (AF3, Qwen2-Audio, Qwen-Omni, SALMONN) across emotion recognition (IEMOCAP), open-ended SQA (LibriSQA), and multi-choice audio understanding (MMAU-speech), we find that the depth and strength of alignment reflect each model's audio-encoder design and the acoustic-versus-semantic demands of the task, and that ALAS tracks but does not duplicate task accuracy, exposing models that score well without genuinely grounding in the audio. We release ALAS as an open-source library so that practitioners can probe their own Speech-LLMs or try it on new tasks.

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17.

arXiv (CS.CL) 2026-06-16 DOI: arXiv:2507.00783

Generative AI and the future of scientometrics: current topics and future questions

作者:

Benedetto Lepori↗Jens Peter Andersen↗Karsten Donnay↗

In this paper, we contribute to the debate on generative artificial intelligence (GenAI) in scientometrics. We argue that moving from a trial-and-error approach to an explainable and actionable use requires a principled understanding of strengths and weaknesses of GenAI as compared with other techniques and with human judgment. To this end, we introduce a conceptual framework based on the distinction between the semantic dimensions of texts, i.e. the meanings attributed to words, and their pragmatic dimension, i.e. their embedding within communicative situations. We leverage this framework to interpret the results of applications of GenAI in scientometrics and to provide guidance to users. Specifically, we conclude that key parameters to be considered are the nature of the task, the level of granularity of the analysis and whether the goal was descriptive, inferential or evaluative. These parameters lead to different strategies for using GenAI and human-machine integration. Finally, we suggest that, by generating large amounts of scientific language, GenAI might affect textual characteristics used to measure science, such as authors, words, and references. We argue that careful empirical work and theoretical reflection will be essential to remain capable of interpreting the evolving patterns of knowledge production in the age of AI.

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18.

bioRxiv (Bioinfo) 2026-06-24 DOI: HASH:4689d66f47d04fd8365c593df0b47aa8

BATTLE-AMP: Benchmarking Antimicrobial Peptide Predictors

作者:

Szymczak↗Bukała↗Zarzecki↗Sala↗Borisek↗Fadavi↗Olayo-Alarcon↗Sroka↗Colome-Tatche↗Gambin↗L. Müller↗Setny↗…

As antimicrobial resistance outpaces antibiotic development, antimicrobial peptides (AMPs) have emerged as a promising class of alternative antibacterials, and computational predictors are increasingly used to prioritize AMP candidates. Such predictors are typically evaluated on binary AMP/non-AMP classification, which does not test whether they can identify peptides with clinically relevant potency against specific pathogens. We present BATTLE-AMP, a benchmarking framework that evaluates AMP predictors against experimentally measured minimum inhibitory concentrations (MICs) across clinically relevant bacterial species and strains. We surveyed 48 published methods, finding fewer than 25% reproducible, and benchmarked 10 model families (21 variants) using experimental MIC data, synthetic sequence perturbations, activity cliff analyses, and all-atom molecular dynamics (MD) simulations. Four findings emerge: (i) models trained on MIC data outperform binary classifiers regardless of architecture; (ii) the best model depends on the target pathogen, so model selection must be guided by the biological question; (iii) most models cannot distinguish active peptides from inactive sequences with identical amino acid composition; and (iv) activity cliffs remain unresolved by both machine learning and MD, marking a limit of current computational methods. BATTLE-AMP is released as an open Snakemake framework at https://github.com/szczurek-lab/battleamp-snakemake for benchmarking new models and scoring novel candidate libraries.

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19.

arXiv (CS.CL) 2026-06-15 DOI: arXiv:2606.14674

AgentSpec: Understanding Embodied Agent Scaffolds Through Controlled Composition

作者:

Jixuan Chen↗Jianzhi Shen↗Haoqiang Kang↗Zhi Hong↗Qingyi Jiang↗Soham Bose↗Yiming Zhang↗Leon Leng↗Amit Vyas↗Lingjun Mao↗Siru Ouyang↗Kun Zhou↗…

LLM agents are increasingly built not as single model calls, but as scaffolded systems that combine reasoning, memory, reflection, action execution, and learning. While such scaffolds often improve performance, they are often embedded in tightly coupled pipelines, making it difficult to isolate component contributions, compare alternative designs, or understand how module interactions shape agent behavior. We introduce AgentSpec, a modular specification framework that represents embodied agents as typed compositions of reusable policy components with standardized interfaces. AgentSpec standardizes the interfaces among perception, memory, reasoning, reflection, action, and optional learning, enabling components to be swapped and recombined under controlled conditions. We instantiate this framework across DeliveryBench, ALFRED, MiniGrid, and RoboTHOR, and analyze reasoning, memory, reflection, and reinforcement-learning modules across model backbones. Our results show that agent performance is governed by scaffold compatibility and interaction effects rather than isolated module strength. In particular, structured multi-granularity memory improves long-horizon state tracking, reasoning and memory interact non-uniformly across environments, reflection trades off correction and cost, and RL-trained policies compose best when optimized with deployment-time scaffold structure. AgentSpec provides a controlled foundation for studying, comparing, and designing composable LLM agents. Our code, baselines and interactive playground are publicly available at https://agentspec-embodied.github.io.

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20.

arXiv (CS.AI) 2026-06-24 DOI: arXiv:2606.24089

DynaWM: Dynamics-Aware Distillation with World Model and Momentum Targets for Smooth Locomotion over Continuous Stairs

作者:

Haidong Hou↗Zhangguo Yu↗Hengbo Qi↗Jianlin Zhang↗

arXiv:2606.24089v1 Announce Type: cross Abstract: Recent advances in control have enabled bipedal-wheeled robots to traverse slopes and single-step obstacles, yet long staircase traversal remains challenging as current teacher-student frameworks suffer from weakened dynamics-aware representations and incomplete terrain geometry encoding. To bridge this gap, we propose DynaWM, a dynamics-aware representation learning framework. To enhance terrain encoding capability and enable transparent assessment, we introduce a world model as a regularizer to enforce forward-dynamics awareness, preserving comprehensive terrain geometry while facilitating hierarchical encoding visualization. To stabilize knowledge transfer, we employ a momentum target encoder to provide consistent distillation targets, preventing dimensional collapse from non-stationary teacher updates. Evaluation of the learned representations through Principal Component Analysis (PCA) visualization and quantitative metrics reveals that our encoder hierarchically captures terrain geometry with higher terrain encoding capability, leading to enhanced terrain adaptability and motion smoothness. Experimental results in simulation and real hardware demonstrate that our method achieves superior terrain adaptability and motion smoothness, enabling bipedal-wheeled robots to overcome diverse continuous stairs, as shown in Fig. 1.

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21.

arXiv (CS.LG) 2026-06-24 DOI: arXiv:2508.12042

FAIRVAR: Fair Federated Learning via Variance Regularization

作者:

Zahra Kharaghani↗Ali Dadras↗Tommy L\"ofstedt↗

arXiv:2508.12042v3 Announce Type: replace Abstract: Federated learning (FL) allows collaborative training of machine learning models across multiple parties without sharing raw data. However, heterogeneous data can cause some clients to have disproportionate influence on the global model, leading to disparities in their performance. Fairness, understood as reducing these disparities, is therefore a crucial concern in FL and has been addressed in various ways. We studied performance equitable fairness in FL, where the goal is to minimize performance disparities across clients. We evaluated several existing fairness-aware methods and introduce here a new gradient-variance-regularized method, implemented in two variants: FairGrad (approximate) and FairGrad* (exact). We theoretically characterize the connections between these methods and, empirically, on heterogeneous benchmarks, show that FairGrad and FairGrad* consistently improve fairness by reducing variance in client accuracies, while maintaining competitive or improved mean performance compared to existing fairness-aware baselines.

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22.

arXiv (CS.LG) 2026-06-11 DOI: arXiv:2606.11490

OmniLoc: A Geometry-Aware Foundation Model for Anchor-Free UE Localization Across Diverse Indoor Environments

作者:

Lei Chu↗Yuning Zhang↗Omer Gokalp Serbetci↗Anushka Katiyar↗Bassel Abou Ali Modad↗Andreas F. Molisch↗

arXiv:2606.11490v1 Announce Type: new Abstract: Indoor localization from wireless measurements remains challenging in large-scale deployments due to substantial variation in building geometry, the set of detectable access points (APs), and the heterogeneity of received signals. Existing learning-based methods often perform well only in limited settings and degrade under environmental shifts, making robust anchor-free localization across diverse indoor environments notoriously difficult. In this paper, we present OmniLoc, an environment-interactive foundation model for anchor-free user equipment localization across diverse indoor environments. To the best of our knowledge, OmniLoc is the first foundation-model-based approach built directly on wireless measurements for this task. OmniLoc is built on three key designs. First, a unified input tokenization module converts heterogeneous wireless measurements into a common representation that is more amenable to learning. Second, a geometry-aware Transformer performs AP-aware feature extraction by emphasizing dominant APs while aggregating complementary evidence from supporting APs. Third, a geometry-aware location estimation module conditions regression on geometric embeddings to produce geometrically consistent location predictions. We evaluate OmniLoc on both a large-scale in-house dataset and a public benchmark dataset. Results show that OmniLoc significantly outperforms existing methods, consistently improves existing backbones when its design components are integrated, and demonstrates strong generalization in cross-environment evaluations.

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23.

arXiv (CS.CV) 2026-06-25 DOI: arXiv:2606.25547

Efficient Cross-Scale Invertible Hiding Network with Spatial-Frequency Collaboration and Non-Invertible Mechanism

作者:

Junxue Yang↗Xin Liao↗

Image hiding aims to conceal image-level messages within cover images at the same resolution. Invertible neural networks (INN)-based image hiding has emerged as an important branch. It treats concealing and revealing as a pair of inverse problems on image domain transformation and uses INN's forward and backward processes to address them. Due to architectural constraints, existing INN-based methods suffer from single-scale and single-domain feature extraction and limited nonlinear representation capability, resulting in inferior image quality. To mitigate these limitations, we propose an efficient cross-scale invertible hiding network with the spatial-frequency collaboration and the non-invertible mechanism, termed CrosInv. CrosInv exploits cross-scale and spatial-frequency collaborative features while enhancing nonlinear representation. Specifically, we introduce a cross-scale invertible module that bijectively maps inputs to cross-scale representations. To effectively integrate spatial and frequency information, the cross-scale invertible module employs pixel shuffle, Haar wavelet transformation, and their inverse operations for scale transformation. Furthermore, a non-invertible cross dense module is integrated to enhance the nonlinearity. Comprehensive experiments verify the effectiveness and superiority of the proposed CrosInv.

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24.

arXiv (CS.LG) 2026-06-18 DOI: arXiv:2606.19105

Smoothness-Based Derandomization of PAC-Bayes Bounds

作者:

Alexandre Lemire Paquin↗Brahim Chaib-Draa↗Philippe Gigu\`ere↗

arXiv:2606.19105v1 Announce Type: new Abstract: We study PAC-Bayes derandomization for smooth loss functions. Our goal is to obtain generalization bounds that hold with high probability for deterministic predictors by exploiting smoothness properties of both the loss and the predictor class. We show that passing from the Gibbs predictor to the deterministic predictor at the posterior mean has a precise cost, given by the generalization gap of the Jensen gap class. We control this class through its Rademacher complexity, leading to bounds for deterministic predictors that involve flatness quantities expressed in terms of parameter Jacobians and Hessians of the score map. The framework applies to both bounded and unbounded smooth loss functions, and we specialize the results to linear predictors and smooth neural networks. Finally, the Jacobian and Hessian quantities appearing in the theory motivate a practical regularizer. For BatchNorm networks, we compute this regularizer with respect to effective BatchNorm weights obtained by folding the BatchNorm transformation into the adjacent affine weights. Experiments on CIFAR-10 illustrate the behavior of this regularizer under different batch sizes.

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25.

arXiv (CS.AI) 2026-06-16 DOI: arXiv:2606.15306

LatentGym: A Testbed For Cross-Task Experiential Learning With Controllable Latent Structure

作者:

Daksh Mittal↗Tommaso Castellani↗Thomson Yen↗Naimeng Ye↗Fangyu Wu↗Minghui Chen↗Tiffany Cai↗Emmanouil Koukoumidis↗William Zeng↗Hongseok Namkoong↗

arXiv:2606.15306v1 Announce Type: cross Abstract: We envision continually learning agentic systems that become more useful over time: as they encounter sequences of related tasks, they should infer the hidden structure shared across those tasks and use it to improve future decisions. This cross-task experiential learning capability is pivotal in domains such as personalization and interactive assistance, but existing training/evaluation frameworks do not provide shared, controllable latent structures and cannot measure whether or why agents improve. We introduce LatentGym: a controllable suite in which each environment is organized around a ground-truth latent variable governing the structure across tasks. Our construction yields metrics that separate exploration (whether the agent's actions gather information about the latent) from exploitation (whether the agent uses what it has gathered). We demonstrate our suite on empirical studies addressing three questions: how and why frontier models fail to adapt across related tasks; whether post-training on related task sequences improves general cross-task adaptation, and where those gains come from; and how design choices such as inter-task feedback shape training dynamics and generalization. Together, these results establish a controlled foundation for studying how LLM agents learn from experience across tasks, and for designing agents that adapt more reliably in sequential, personalized, and interactive settings.

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