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01.
arXiv (CS.AI) 2026-06-11

End-to-End Machine Learning for Depressive State Classification via EEG and fNIRS

arXiv:2606.11555v1 Announce Type: cross Abstract: The escalating demand for mental healthcare, driven by rising societal stress, highlights the limitations of traditional psychiatric diagnostics. Conventional methods - relying primarily on clinical interviews and patient self-reports - are inherently vulnerable to subjective bias and the varying empirical judgment of practitioners. To address the need for quantitative evaluation, biological signal-based detection, including electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS), has emerged as a promising objective alternative. Such technology is particularly vital for identifying latent depressive states that may be unrecognized by the subjects themselves. Furthermore, in aging populations, the high comorbidity between depression and dementia necessitates early differentiation to prevent mutual symptom exacerbation and maintain Quality of Life (QoL). This pilot study of eleven healthy students establishes a framework for biological signal-based depression detection, serving as a foundational step toward automated, objective diagnostic tools for clinical use.

02.
arXiv (CS.LG) 2026-06-18

Protein-Based Fish Species Identification: Dataset, Models, and Insights from Native Bangladeshi Fish

arXiv:2606.18302v1 Announce Type: cross Abstract: Correct identification of fish species is highly significant for food security, economic development, and climate resilience in Bangladesh. Protein sequences directly reflect functional and evolutionary constraints which are important for species authentication and biodiversity monitoring. Yet there exists no benchmark for native Bangladeshi fish species identification from protein sequence. In this study, we addressed this gap by introducing the first curated dataset for nine native Bangladeshi fish species of 2845 high quality protein sequences. We also established the first protein sequence classification baseline for this domain through a systematic benchmarking of seven architectural paradigms. Moreover, we propose a realistic deployable novel hybrid architecture of MotifCNN and Transformer with Terminal-Aware Positional-Encoding (MotifCNN-Transformer+TA-PE). Our novel architecture achieves 79.80% accuracy with macro-F1 of 0.80. The highest 83.04% accuracy is achieved by finetuned protein language model ProtBERT that has 420M parameters and requires dual 16GB GPUs for inference. According to McNemar's test, ProtBERT's 3.24% accuracy gain over our MotifCNN-Transformer+TA-PE is statistically insignificant (p = 0.1120). Our novel architecture beats it among six of the nine classes in per class identification. Also our MotifCNN-Transformer+TA-PE is approximately 5x faster, 42x smaller, and supports 16x larger batch size than ProtBERT and has GPU free inference, making it more practical for deployment in resources constrained areas such as rural Bangladesh. Beyond this, our foundational work shows effects of phylogenetic relationships on sequence similarity and establishes pathways for fisheries management, food authentication and biodiversity conservation in South Asia's protein dependent economy.

03.
arXiv (math.PR) 2026-06-24

Typical geometry of self-repelling polymers in a constant force field

arXiv:2606.24352v1 Announce Type: cross Abstract: We study a general class of self-repelling polymers on $\mathbb Z^2$, including the simple random walk, the self-avoiding walk and the repulsive Domb-Joyce model, in the presence of a constant force field acting on each monomer. Conditioning the polymer to have fixed length and fixed endpoints, we identify the limiting free energy and prove that typical trajectories concentrate exponentially near a deterministic macroscopic shape. This shape is characterized as the unique minimizer of a variational problem and can be interpreted as a geodesic of a height-dependent Finsler metric. We also analyze two limiting regimes with universal features: for small field strength, in the symmetric case, the geodesic is close to a classical catenary, while for large field strength it converges to a universal polygonal shape governed by the nearest-neighbor lattice constraint.

04.
arXiv (CS.AI) 2026-06-11

SirenFNO: Efficient and Full Frequency Learning of Fourier Neural Operators

arXiv:2606.11518v1 Announce Type: cross Abstract: Fourier neural operators (FNOs) are effective and efficient surrogates for approximating solutions of PDEs and generalize across discretizations. However, owing to the reliance on frequency truncation to maintain learning efficiency of FNOs, empirical studies suggest that FNOs exhibit spectral bias toward low-frequency information, which may hinder the learning capability especially for certain PDEs with strong high-frequency oscillations. To address this limitation, we propose SirenFNO, a novel framework that leverages sinusoidal representation networks (SIRENs) to learn implicit neural representations and performs mode-wise kernel parameterization. Our SIREN parameterization learns a full-grid spectrum with a constant and discretization-independent parameter count, thereby eliminating the need for frequency truncation. We further extend SirenFNO with functional tensor decompositions to enhance parameter and learning efficiency. Empirical results show that our SirenFNO consistently outperforms FNO with approximately $4$ to $15$ times parameter reductions with preserved discretization invariance, and our functional decomposition variants obtain performance improvements with a maximum of $73$ times fewer parameters across multiple PDE benchmarks.

05.
arXiv (CS.AI) 2026-06-17

Conservation Laws for Modern Neural Architectures

arXiv:2606.17816v1 Announce Type: cross Abstract: Understanding gradient descent dynamics is key to explaining the success of over-parameterized models, where implicit bias manifests through conservation laws in gradient flow. While such laws are well understood for linear and ReLU networks, they remain largely unexplored for modern architectures. This work develops a unified framework to characterize conservation laws for contemporary models, including feedforward networks with GELU, SiLU, and SwiGLU activations, multihead attention with sinusoidal and rotary positional encodings, and Mixture-of-Experts architectures under diverse gating designs. Our theoretical findings are supported by experiments that validate the predicted invariants.

06.
arXiv (CS.AI) 2026-06-11

LLMs+Graphs: Toward Graph-Native, Synergistic AI Systems

arXiv:2606.11560v1 Announce Type: cross Abstract: Large Language Models (LLMs) have advanced rapidly, but their limitations in structured and multi-hop reasoning underscore the need for graph-native, synergistic artificial intelligence (AI) systems. Graph-structured data underpins critical applications across social, biological, financial, transportation, web, and knowledge domains, making it essential to understand how LLMs can leverage graph computation for grounded, context-rich inference. Three complementary synergies are emerging: LLMs augmented with graph computation for retrieval and reasoning; bidirectional integration between LLMs and knowledge graphs (KGs), where LLMs support KG construction and curation while KGs enforce semantic constraints and factual consistency; and AI agents strengthened by graph algorithms for planning, decision making, and multi-step reasoning. In parallel, LLMs introduce new capabilities for graph data management and graph machine learning (ML) through natural language interfaces and hybrid LLM-graph neural network (GNN) pipelines. This tutorial synthesizes the algorithms, systems, and design principles driving these converging directions, offering data science and data mining researchers a unified perspective on integrating LLMs, graph data management, graph mining, graph ML, and agentic computation into next-generation graph-native AI systems.

07.
arXiv (CS.CV) 2026-06-24

Tri-Efficient Transfer Learning for Point Cloud Videos

While point cloud foundation models have significantly advanced point cloud video understanding, existing parameter-efficient fine-tuning (PEFT) methods still suffer from two critical limitations: prohibitive annotation costs for large-scale point cloud datasets and severe memory bottlenecks. In this paper, we aim to mine richer supervision signals from existing data rather than blindly scaling datasets. A further key principle is that the memory footprint of fine-tuning must be drastically reduced compared to full fine-tuning, which remains elusive for current PEFT techniques. Driven by these challenges, we identify three core desiderata: data-, parameter-, and memory efficiency, and present PoinTriE, a unified framework that excels along all three dimensions. For pre-training, pseudo-motion trajectories are synthesized via rigid transformations, paired with text corpora and 2D projections derived from raw point clouds. We then propose a Geometric-Motion Duality Network optimized via multimodal contrastive learning, rigid rotation prediction, and motion distribution divergence to produce dense self-supervision. During fine-tuning, we freeze the pretrained backbone and only update a lightweight Spatio-temporal Side Network built with LoRA units. Equipped with a gradient flow masking strategy, PoinTriE simultaneously reduces memory consumption and parameter overhead. Extensive experiments confirm that PoinTriE establishes new state-of-the-art results on action recognition and semantic segmentation tasks.

08.
arXiv (CS.LG) 2026-06-25

Structured Approximations of Measures

arXiv:2310.09149v3 Announce Type: replace-cross Abstract: We study the approximation of probability measures in the Wasserstein-$p$ distance by structured classes of approximators, motivated by applications in imaging, machine learning, and physical measurement under sensor constraints. We obtain three sets of results. First, for measures with densities bounded away from zero on a bounded Lipschitz domain $\Omega$, we prove that any approximation scheme for functions in $\mathrm{L}_p(\Omega)$ transfers, with linear rate, to a corresponding approximation scheme for measures in $\mathrm{W}_p(\Omega)$. The argument applies a theorem of Bogovskii on regularity of solutions to the continuity equation in the Benamou-Brenier formulation of optimal transport. We exhibit concrete approximation schemes (polynomials, shift-invariant spaces, cardinal interpolation with radial basis functions, kernel density estimators, and piecewise approximations on nonuniform Voronoi partitions) that fit the framework. As a matter of independent interest, we prove a negative Sobolev lower bound that generalizes existing bounds from $p=2$ to all $p\in(1,\infty)$. We also consider deterministic bounds for discrete approximations to arbitrary measures in terms of the mesh norm of a quasi-uniform set of points. We specialize these bounds to show that compactly supported measures admit a deterministic $N$-term approximation $\mu_N$ such that $\mathrm{W}_p(\mu,\mu_N) = O(N^{-\frac{1}{d}})$ for all $d\geq 1$, which matches the asymptotic optimal quantizer rate. We also extend these results to non-compactly supported measures with appropriate tail decay.

09.
arXiv (CS.LG) 2026-06-16

Understanding Latent Diffusability via Fisher Geometry

arXiv:2604.02751v2 Announce Type: replace Abstract: Diffusion models often degrade in latent spaces, yet the formal causes remain poorly understood. We quantify latent-space diffusability via the rate of change of the Minimum Mean Squared Error (MMSE) along the diffusion trajectory. Our framework decomposes this MMSE rate into contributions from Fisher Information (FI) and Fisher Information Rate (FIR). We demonstrate that while global isometry ensures FI alignment, FIR is governed by the interplay between encoder and data geometries. Our analysis decouples diffusion degradation into four penalties: dimensional compression, tangential distortion, high-frequency encoder curvature, and intrinsic data curvature. We derive theoretical conditions for FIR preservation to ensure stable diffusability. Experiments across diverse autoencoding architectures demonstrate the implications of our theoretical bounds. We establish FI and FIR as a comprehensive analytical framework for understanding latent diffusability.

10.
arXiv (CS.LG) 2026-06-16

Semantic DLM+: Improving Diffusion Language Models through Bias-variance Trade-off in Transition Kernel Design

arXiv:2606.15327v1 Announce Type: new Abstract: Diffusion Language Models (DLMs) have demonstrated strong scaling capacity as alternatives to autoregressive language models. However, their performance is highly sensitive to the choice of transition kernels, and poorly designed kernels can lead to issues like training instability, slow convergence, and biased sampling. In this paper, we study this sensitivity through a principled analysis of generalization error and identify three critical factors: asymptotic bias (difficulty in approximating the posterior distribution), exposure bias (error propagation during sampling), and optimization variance induced by kernel dispersion. We further compare different transition kernels: masking diffusion yields sparse and easier posterior-approximation targets, while uniform diffusion provides stronger sampling-side repair but induces harder approximation. Motivated by this trade-off, we revisit a previously overlooked variant, semantic DLM (SemDLM), where the transition kernel corrupts tokens to neighborhoods that are semantically similar. Our theory suggests that SemDLM can serve as a plausible middle ground by reducing the posterior approximation difficulty of uniform diffusion while retaining repair ability. However, we find that SemDLM suffers from a semantic basin problem, where sampling repeatedly stays within a semantic region and produces low-diversity text. To address this, we propose SemDLM+, which adds a global transition and a semantic-frequency penalty during sampling. Experiments on LM1B and OpenWebText show that SemDLM+ improves training dynamics and achieves competitive language modeling and generation quality with satisfactory diversity.

11.
arXiv (CS.CV) 2026-06-11

OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models

High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers. We introduce OpenMedReason, a large-scale, open multimodal medical reasoning corpus comprising approximately 450K image-question-answer instances whose reasoning traces are primarily derived from curated biomedical, human-authored scientific articles. OpenMedReason provides high-fidelity supervision beyond synthetic chains of thought, covering diverse medical domain vision modalities such as radiological scans, microscopic images, visible light photographs, charts, and others. We complement it with OpenMedReason-Bench, a held-out benchmark that allows fine-grained evaluation of LVLMs along three complementary axes of capability, including perception, medical knowledge, and rationale, enabling diagnostic evaluation beyond final-answer accuracy. OpenMedReason is a rich training resource that exhibits its effectiveness in both supervised fine-tuning (SFT) and reinforcement-based alignment. Training with OpenMedReason yields a 20% average improvement in VQA accuracy over the base model and achieves performance within 4.2% of the strongest comparable-scale medical LVLMs. Fine-grained performance analysis confirms that the gains are not concentrated in any single axis: OpenMedReason improves perception, medical knowledge, and rationale jointly, and its reasoning traces are preferred over those of the base model in 86.1% of pairwise comparisons. We release the code and dataset at huggingface.co/datasets/neginb/OpenMedReason.

12.
medRxiv (Medicine) 2026-06-18

A Brain-Aging Transcriptomic Signature Reclassifies WHO Glioma Grade and Predicts Survival Independently of IDH Status: A Multi-Cohort Study

Background Despite WHO grade and IDH status, significant survival differences remain in diffuse gliomas. We hypothesized that a brain-aging transcriptomic signature, reflecting neuroinflammation, myeloid infiltration, and synaptic loss, would independently predict survival and allow for molecular reclassification. Methods A neurodegeneration score was derived via PCA of brain MRI volumes from 1,057 OASIS-3 subjects and projected onto 888 TCGA-LGG/GBM (discovery) and 693 CGGA gliomas (validation). A 14-gene signature of glial/myeloid (GFAP, AQP4, TYROBP, TREM2, C1QA, CD68, ITGAM) and neuronal (SYP, DLG4, GRIN1, GRIA1, SNAP25, SYN1, RBFOX3) genes were computed. Elastic-net Cox regression identified a 3-gene panel (C1QA, CD68, GRIA1). Kaplan-Meier, multivariate Cox, decision curve, and single-cell RNA-seq analyses were performed. Results High brain-aging scores predicted poorer overall survival (p < 0.0001) and remained an independent prognostic factor after adjusting for WHO grade and IDH status (z = 4.72, p < 0.001); chronological age was non-significant (p = 0.231). In IDH-mutant gliomas, significance was confirmed in both cohorts (TCGA p = 0.027; CGGA p < 0.0001). Bidirectional reclassification showed high-risk Grade 2 tumors with Grade 3-like survival (p = 0.00089), and indolent Grade 3 tumors resembling Grade 2 by Ki-67. Single-cell RNA-seq confirmed macrophage localization of signature genes; DCA demonstrated net benefit over grade alone at 5-30% probability thresholds. Conclusions A brain-aging transcriptomic signature independently predicts glioma survival beyond WHO grade and IDH status, validated in an independent Chinese cohort, with clinical utility for identifying high-risk Grade 2 and sparing over-treatment of indolent Grade 3 tumors.

13.
arXiv (CS.LG) 2026-06-24

FuseSampleAgg: One-Pass Neighborhood Estimation for Budgeted Knowledge-Graph Refresh and Validation

arXiv:2511.13645v2 Announce Type: replace Abstract: Operational knowledge-graph (KG) pipelines in networking and cybersecurity increasingly need to refresh embeddings under strict time, memory, and audit budgets, especially as curated feeds and LLM-assisted extraction accelerate KG updates. A recurring per-step cost in mini-batch KG learning is neighborhood-context estimation: uniform neighbor sampling without replacement followed by mean aggregation. Common frameworks implement this estimator through sampled-subgraph materialization and intermediate feature gathers, adding kernel launches, allocator pressure, and transient memory spikes. We present One-Pass Neighborhood Estimation, a fused PyTorch CUDA operator that samples neighbors and directly emits the sampled-neighborhood mean, avoiding explicit block construction while preserving GraphSAGE-mean semantics for the same sampled neighbor IDs. It supports seed-controlled sampling and optional saved-index replay for reproducible validation and regression testing. Across large-graph mini-batch workloads, it improves FP32 end-to-end step latency by 2.24x-3.48x over tuned DGL baselines and reduces transient GPU memory by up to 160x in our measurements. On OGB KG completion benchmarks such as WikiKG2 and BioKG, it reduces step time and peak VRAM while matching ranking quality within seed variability, improving time-to-quality for budgeted KG refresh.

14.
arXiv (CS.CV) 2026-06-17

RAVA: Retrieval-Augmented Viewpoint Alignment for Subject-Driven Image Generation

Reference-driven image generation has made rapid progress on identity preservation, but reliable viewpoint control across different subjects remains poorly understood. The difficulty is not merely generating a new image of the target subject: the model must infer the implicit viewpoint of one subject and transfer it to another subject using only image-level evidence, without camera poses, depth, or ray-based conditions. In this setting, existing generators conditioned on multiple image references often rely on spurious semantic correlations, which lead to viewpoint drift, part-level structural mismatches, and missing or unsupported target-specific content. We formulate this challenge as cross-subject viewpoint alignment and propose RAVA, a retrieval-augmented framework that supplies explicit geometric evidence before generation. RAVA first learns a cross-instance viewpoint embedding that retrieves target-subject images aligned with the anchor viewpoint, then applies a LogDet-based subset selection strategy to retain a compact reference set that is both view-consistent and structurally complementary. The selected references are finally consumed by a fine-tuned multi-reference image generator. Experiments show that generic semantic embeddings are nearly random for this task, while the proposed retriever substantially improves viewpoint retrieval quality. On cross-subject generation, RAVA consistently outperforms zero-shot baselines and stronger retrieval alternatives under the same generation backbone. These results indicate that cross-subject viewpoint alignment benefits from retrieval-augmented geometric grounding rather than relying on end-to-end generation alone.

15.
arXiv (CS.CV) 2026-06-17

Similarity-based representation factorization for revealing interpretable dimensions in representational data

The study of representations is widespread across fields, including neuroscience, psychology, and artificial intelligence. While representations are often studied and compared through similarities between stimuli, current methods provide only limited access to the dimensions that shape these representations and are often limited in interpretability. To overcome these challenges, here we introduce Similarity-Based Representation Factorization (SRF), a general computational method for recovering low-dimensional, non-negative, interpretable embeddings from similarity matrices derived from measured data. Across simulations and many neural, behavioral, and computational datasets, SRF recovers interpretable dimensions from diverse forms of representational data, even for very sparsely sampled, incomplete data. The dimensions derived from these datasets match those obtained by task-specific models, predict independent behavioral properties, improve exploratory analysis, and offer higher power for confirmatory hypothesis testing than comparing similarity matrices. Together, these results establish SRF as a general-purpose method with broad applications for uncovering, understanding, and using the dimensions underlying representations.

16.
arXiv (CS.LG) 2026-06-16

Bridging data-driven priors via the score function for posterior sampling – Comparative review and experimental study

arXiv:2606.14800v1 Announce Type: cross Abstract: This paper reviews how a diverse set of popular data-driven priors commonly used in Bayesian inverse problems can be unified through their respective score functions. By framing these priors under this common perspective, we show that they can benefit from their straightfoward and effective integration into a recently proposed sampling algorithm. The applicability of this common framework is illustrated by considering several data-driven priors, namely regularization-by-denoising, normalizing flow-based priors, score-based generative models, and convex-ridge regularizers. For these four particular priors, the performance of the method is evaluated when conducting image inpainting and single image super-resolution. These results, as well as those obtained when restoring real images acquired in a geological context, demonstrate the efficiency of the method. This unified framework proves versatile enough to handle any posterior distribution defined by a broad class of score function-based priors, beyond the specific cases considered in this paper.

17.
medRxiv (Medicine) 2026-06-11

Global population frequencies of NAT2 star alleles observed in three large biobanks

NAT2 is an important pharmacogene which encodes the N-acetyltransferase 2 enzyme that is involved in the metabolism of multiple medications, and variants in this gene can affect patient response to these medications. CPIC has published a clinical guideline for prescribing hydralazine using NAT2 genotypes. Just prior to the guideline, updated NAT2 star allele numbering and definitions were released, differing somewhat from the historical nomenclature. Clinical pharmacogenomic testing panels often test for the most common star alleles, so knowledge of the most common updated NAT2 star alleles is critical for the implementation of the CPIC NAT2/hydralazine guideline. We first determine NAT2 diplotype frequencies from UK Biobank (UKBB) 200k phased genomes, then analyzed allele, diplotype, and phenotype population frequencies from the All of Us Research program, PennMedicine BioBank (PMBB) and UKBB 500k datasets. We found that analyzing NAT2 diplotypes from phased data provides critical information for algorithms designed to predict diplotypes from unphased data. We observed that NAT2*5, *6, and *4 were the most common star alleles in that order, and the top 11 most frequent NAT2 star alleles were the same across all biobanks. However, differences in star allele frequencies across biogeographical populations were observed. The largest difference led to a higher frequency of NAT2 poor metabolizer phenotypes as compared to rapid and intermediate metabolizer phenotypes in all global populations except in the EAS population, where NAT2 poor metabolizers were in the minority.

18.
arXiv (CS.AI) 2026-06-16

From Overload to Convergence: Supporting Multi-Issue Human-AI Negotiation with Bayesian Visualization

arXiv:2603.22766v2 Announce Type: replace-cross Abstract: As AI systems increasingly mediate negotiations, understanding how the number of negotiated issues impacts human performance is crucial for maintaining human agency. We designed a human-AI negotiation case study in a realistic property rental scenario, varying the number of negotiated issues; empirical findings show that without support, performance stays stable up to three issues but declines as additional issues increase cognitive load. To address this, we introduce a novel uncertainty-based visualization driven by Bayesian estimation of agreement probability. It shows how the space of mutually acceptable agreements narrows as negotiation progresses, helping users identify promising options. In a within-subjects experiment (N=32), it improved human outcomes and efficiency, preserved human control, and avoided redistributing value. Our findings surface practical limits on the complexity people can manage in human-AI negotiation, advance theory on human performance in complex negotiations, and offer validated design guidance for interactive systems.

19.
arXiv (CS.LG) 2026-06-25

Do Prompt-Elicited Trajectories Reflect Training-Time Reward Hacking? A Systematic Study on Monitoring Trainig-Time Reward Hacking in Code Generation

arXiv:2604.23488v2 Announce Type: replace Abstract: Reward hacking in code generation, where models exploit evaluation loopholes to obtain high reward without correctly solving the intended task, poses a critical challenge for Reinforcement Learning (RL) and the deployment of reasoning models. Existing studies often rely on explicitly prompted hacking trajectories, but it remains unclear whether monitors trained on such data can detect reward hacks that arise without direct hacking instructions during RL training. In this work, we introduce Trace-and-Amplify, a framework for scalable curation of reward-hacking trajectories that arise during RL training without explicit hacking instructions. The framework uses unit-test tracers to identify hacking solutions when they occur and retains such trajectories for monitor training and evaluation. Through controlled comparisons between monitors trained on prompt-elicited hacking trajectories and training-time reward-hacking trajectories collected by Trace-and-Amplify, we find that (1) prompt-elicited-data-trained monitors often fail to generalize to trajectories curated by our framework, and (2) monitors trained on our Trace-and-Amplify trajectories demonstrate stronger generalizability to unseen hacking types. Our results indicate that prompted reward hacking data may not fully reflect training-time reward-hacking behaviors, and that relying solely on these data can lead to misleading conclusions. Codebase is available at https://github.com/LichenLillc/CoTMonitoring.git

20.
arXiv (CS.LG) 2026-06-17

MorphStrata: Layer-Specific Perturbations for Generating Morphence Students in Time-Series Moving Target Defense

arXiv:2606.17435v1 Announce Type: new Abstract: Time-series forecasting models remain vulnerable to gradient-based adversarial attacks while existing defense mechanisms typically incur a trade-off in robustness for bounded response and compute cost. The problem is pronounced in Moving Target Defense where maintaining multiple randomized model instances substantially exacerbates the training overhead. In this work, we introduce MorphStrata, a student generation strategy with selective, layer-specific stochastic noise injection that extends the traditional Morphence defense. MorphStrata uses a Transformer backbone as the teacher and perturbs randomly selected architectural blocks to create structured heterogeneity across student models in response to varied data distributions and threat models. We evaluate against vanilla Transformer and Morphence backbones on a suite of benchmarks including the Jena Climate, Electricity Load Diagrams, and Appliances Energy Prediction using FGSM, BIM and PGD attacks across multiple attack strengths. Across datasets and attack regimes, the proposed ensemble maintains comparable adversarial RMSE. Specifically, for high entropy, periodic datasets as in the case of the AEP data, MorphStrata achieves the lowest RMSE across all attacks and perturbation budgets, improving over the static baseline by up to 24.11% and 97.97% under FGSM and BIM respectively at an epsilon value of 0.5 over 30 randomized trials. Targeting the layers to generate MorphStrata students accounts for less than 1% increase in train-times over the Morphence MTD baseline for most of the experiments, while accounting for double digit gains in adversarial RMSE reduction. We also observe a positive correlation between higher pairwise L2 distance (among generated students) and overall defense effectiveness. In summary, MorphStrata maintains adversarial robustness as an MTD defense at marginal cost deltas when compared to existing baselines.

21.
arXiv (CS.LG) 2026-06-16

Multiscale Hypersonic Boundary Layer Reconstruction via Spectral Binning and Subdomain-wise Conditional Diffusion

arXiv:2606.15023v1 Announce Type: cross Abstract: We propose a multiscale probabilistic reconstruction framework for hypersonic Couette flow, where near-wall states are inferred from limited top-wall observations using conditional diffusion model. The boundary layer is divided into overlapping wall-normal subdomains, and a single height- and Mach-conditioned Elucidating Diffusion Model (EDM) is trained jointly for M=6,7,8 to sample velocity, density, pressure, and temperature fields conditioned on a top-wall boundary slice. A soft overlap inpainting strategy assembles subdomain predictions into full-volume reconstructions while maintaining inter-subdomain continuity and small-scale variability. To improve the spectral fidelity of the generated fields, we introduce a novel bounded binned spectral power (BSP) loss that preserves high-wavenumber content while remaining numerically stable across the diffusion noise schedule. Validation against direct numerical simulation data shows that the model recovers instantaneous structures, spectra, statistical profiles, correlations, and wall quantities across all training Mach numbers, while providing spatially structured uncertainty estimates. The reconstructed Mach-conditioned profiles also collapse under the Trettel-Larsson transformation, indicating consistency with compressibility scaling. These results establish the domain decomposed conditional diffusion model with a bounded binned spectral loss as an effective probabilistic surrogate for near-wall reconstruction in hypersonic wall-bounded turbulence.

22.
arXiv (quant-ph) 2026-06-24

Rapid Cavity-Based Mid-Circuit Measurement and Feedforward in a Neutral Atom Array

arXiv:2606.24869v1 Announce Type: new Abstract: Measuring part of a quantum system in the midst of its evolution and acting on the result in real time is essential for numerous quantum information protocols. Neutral-atom arrays are a leading platform for quantum information processing, but their mid-circuit measurement-and-feedforward cycle times have remained slow, typically exceeding 1 ms. Here we demonstrate fast mid-circuit measurement and real-time feedforward in an array of atomic qubits coupled to a high-finesse optical cavity. Local light shifts tune individual data qubits out of resonance with the cavity, shielding their coherence, while a near-resonant probe drives a selected qubit whose emission is collected with Purcell enhancement. Mid-circuit measurements of four qubits with sub percent infidelity reduce the coherence of a fifth unmeasured data qubit by less than 2%. We implement real-time feedforward to correct measurement-induced phase shifts and to realize an adaptive circuit for optimal quantum state discrimination and conditional state preparation. Our approach reduces the measurement-and-feedforward cycle time to below 100 $\mu$s and establishes optical cavities as a route to fast control of neutral-atom quantum systems.

23.
arXiv (CS.LG) 2026-06-24

One Ruler: A Same-Hands Re-Evaluation of Bivariate Causal Direction on Tuebingen, with a Parameter-Free Compression Baseline

arXiv:2606.23767v1 Announce Type: new Abstract: Headline accuracies on the Tuebingen cause-effect pairs are routinely compared across papers even though each is measured under its authors' own protocol – different pair subsets, weightings, model-selection, and decision rates. We argue this is the wrong comparison and run the right one: a same-hands re-evaluation in which every method is run by us on the identical 102 pairs, with one strict rule – no tuning and a decision forced on every pair. As a clean reference point we introduce a deliberately minimal baseline: sorted-conditional compression, which feeds quantized, sorted, first-differenced data to an off-the-shelf compressor (bz2) and has zero fitted parameters. Under the common ruler the ranking differs sharply from the literature. Our baseline reaches 74.7% weighted accuracy (p = 3.7e-7); on the same 100 pairs that SLOPE is evaluated on it scores 76.0%, a 1.2-point gap below the authors' own forced-decision SLOPE (77.2%) that is well inside noise (McNemar p = 0.39). A faithful re-run of RECI lands at 70.7% – inside the original authors' reported error bar, not the 77.5% often quoted (which we trace to a mis-copied cell). SLOPE's published 82.4% is a decided-subset figure: scoring the authors' own stored output only on the pairs its significance test chose to answer reproduces 81.7%. Under the common ruler the methods cluster in the low-to-mid 70s and the zero-parameter compressor ties the strongest of them. We document the mechanisms that inflate published figures (test-set model selection, significance-gated abstention) and contribute two further results: compression score magnitude is a model-free confounding flag (p = 2.8e-68), and a pre-registered falsification test fails in an instructive way that bounds the method's theoretical interpretation. Code, pre-registrations, and per-pair outputs are released.

24.
bioRxiv (Bioinfo) 2026-06-11

A systematic imputation framework for sparse, multimodal space biology datasets: application to retinal imaging and omics from the RR9 mission

Space biology experiments are expensive, logistically complex, and inherently limited in sample size, resulting in datasets that are frequently incomplete and highly heterogeneous (2). Missing data is a fundamental barrier to building reliable computational models of how the human body responds to spaceflight. This work introduces a systematic framework for addressing missing data through imputation. We developed a validated four-stage framework for imputation specifically designed to preserve biological signal needed for digital twin development, while quantifying trade-offs in downstream analyses. Using retinal imaging and omics data from the NASA RR9 mission as a case study (9), we demonstrate how to diagnose why data is missing(10), select and optimize appropriate imputation strategies (5,10), and rigorously evaluate whether imputed data remains biologically meaningful. A key finding of this work is that while imputation substantially improves the performance of predictive models, it can simultaneously obscure subtle biological patterns; a critical trade-off that researchers must understand before applying these methods (11). This framework provides practical, actionable guidance for space biologists and data scientists working with sparse, multimodal datasets in space biology, and represents a foundational step toward more complete and reliable data-driven models of human physiology in extreme environments.

25.
arXiv (CS.LG) 2026-06-25

Frequency Domain Reservoir Computing

arXiv:2606.24969v1 Announce Type: new Abstract: While the quadratic sequence-length bottleneck of transformers has fueled a resurgence in recurrent models, effectively capturing complex dynamics requires architectures that balance efficient training with highly expressive latent states. Echo State Networks (ESNs) offer a compelling approach by utilizing fixed recurrent weights to circumvent backpropagation through time, enabling a closed-form training solution. However, achieving the expressivity needed for complex tasks demands large reservoirs, exposing an $\mathcal{O}(N^2)$ state-update bottleneck that prevents ESNs from matching the scale of contemporary recurrent models. To address this limitation, we introduce Frequency Domain Reservoir Computing (FRESCO), an ESN architecture operating entirely in the frequency domain while avoiding domain-shift overheads to achieve $\mathcal{O}(N)$ complexity for dense, non-linear recurrent updates. By employing a novel dimensional zero-padding input embedding, a packed \operatorname{FD}h readout, and a natively applied frequency-domain non-linearity, FRESCO drastically reduces computational costs and energy consumption of training and inference. Furthermore, FRESCO matches the state-of-the-art predictive performance on memory benchmarks, sequential classification, and multivariate long-horizon forecasting, offering a scalable path forward for dense recurrent architectures.