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01.
arXiv (math.PR) 2026-06-25

The relationship between the transition functions of the labeled and unlabeled versions of the infinitely-many-neutral-alleles diffusion model

Authors:
S. N. Ethier↗

arXiv:2606.06739v2 Announce Type: replace Abstract: The transition function of the unlabeled infinitely-many-neutral-alleles diffusion model, as expressed by Zhou (2015), is derived from the transition function of the labeled infinitely-many-neutral-alleles diffusion model, slightly simplifying the derivation by Feng (2010).

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02.
arXiv (CS.AI) 2026-06-17

Riemann-Bench: A Benchmark for Moonshot Mathematics

Authors:
Suhaas Garre↗Erik Knutsen↗Sushant Mehta↗Edwin Chen↗

arXiv:2604.06802v2 Announce Type: replace Abstract: Recent AI systems have achieved gold-medal-level performance on the International Mathematical Olympiad, demonstrating remarkable proficiency at competition-style problem solving. However, competition mathematics represents only a narrow slice of mathematical reasoning: problems are drawn from limited domains, require minimal advanced machinery, and can often reward insightful tricks over deep theoretical knowledge. We introduce Riemann-Bench, a private benchmark of expert-curated problems designed to evaluate AI systems on research-level mathematics that goes far beyond the olympiad frontier. Problems are authored by Ivy League mathematics professors, graduate students, and PhD-holding IMO medalists, and routinely took their authors weeks to solve independently. Each problem undergoes double-blind verification by two independent domain experts who must solve the problem from scratch, and yields a unique, closed-form solution assessed by programmatic verifiers. We evaluate frontier models as unconstrained research agents, with full access to coding tools, search, and open-ended reasoning, using an unbiased statistical estimator computed over 100 independent runs per problem. Our results reveal that all frontier models currently score below 10%, exposing a substantial gap between olympiad-level problem solving and genuine research-level mathematical reasoning. By keeping the benchmark fully private, we ensure that measured performance reflects authentic mathematical capability rather than memorization of training data.

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03.
arXiv (CS.AI) 2026-06-16

CoAgent: Concurrency Control for Multi-Agent Systems

Authors:
Hongtao Lyu↗Dingyan Zhang↗Mingyu Wu↗Xingda Wei↗Haibo Chen↗

arXiv:2606.15376v1 Announce Type: cross Abstract: Multi-agent LLM systems – coding agents, devops agents, document agents – now routinely run several agents in parallel against the same git tree, Kubernetes cluster, or document. As soon as two of them mutate shared state, they enter the regime classical concurrency control has studied for decades, but classical mechanisms fit LLM agents poorly. A single agent transaction spans minutes of inference, read sets are broad and opaque rather than statically inferable, and the live state agents act on admits neither fork nor buffer, so writes take effect the moment they execute. Locks block long inference intervals; OCC abort-and-retry discards minutes of work on every conflict. This paper builds concurrency control on a capability classical transactions lack: the LLM inside each agent can judge whether a conflicting write invalidates its plan, and can repair exactly the operations that depended on it. Control therefore turns advisory: the runtime informs, the agent repairs. Our protocol, MTPO (Monotonic Trajectory Pre-Order), fixes a serialization order at launch, serves each read the order-filtered value, and applies writes speculatively in place; a one-way notification asks an affected reader to re-judge and patch its plan, while the framework mechanically undoes and reorders misplaced writes through the saga-style inverse each tool registers in advance. At quiescence the run is serializable in the pre-decided order. We realize MTPO as CoAgent, toolcall middleware whose privileged ToolSmith grows footprint-declared, undoable tools online. On ten contended workloads, CoAgent stays within 5\% of serial correctness at a $1.4\times$ speedup and near-serial token cost, where 2PL and OCC surrender nearly all concurrency gains; on a bash-only target system, it grows a 25-tool library online and lifts the task pass rate from 45/71 to 63/71 at $0.80\times$ the time and $0.86\times$ the cost.

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04.
arXiv (CS.CV) 2026-06-16

Lesion-DDPM: Lesion-Enhanced 3D Diffusion for MS MRI Synthesis

Authors:
Weidong Zhang↗Yongchan Jung↗Shafayat Mowla Anik↗Furen Xiao↗Vasudevan Janarthanan↗Enkhzaya Chuluunbaatar↗Byeong Kil Lee↗Jeeho Ryoo↗

3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns. This scarcity and variability hinder the development of robust neuroimaging machine learning models and are particularly challenging for generative models that aim to synthesize images while preserving small, sparse lesions. We propose Lesion-DDPM, a 3D conditional diffusion framework for lesion-aware FLAIR synthesis that incorporates multi-level anatomical mask injection together with a lesion-weighted reconstruction loss to emphasize lesion voxels while maintaining global brain structure. Using a curated subset of the MSLesSeg dataset, we compare Lesion-DDPM with representative state-of-the-art GAN- and diffusion-based models, assessing both image-generation metrics and downstream 3D U-Net segmentation. In our experiments, Lesion-DDPM achieved the lowest lesion-region reconstruction error among all methods. In a downstream 3D U-Net lesion segmentation task, a model trained only on Lesion-DDPM-generated scans and evaluated on real MRIs reached a Dice score of 0.616 compared with 0.569 for the best competing synthetic dataset. When Lesion-DDPM images were added to the real training set, the Dice score further increased to 0.685.

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05.
arXiv (math.PR) 2026-06-25

Spectral Collapse Under Geometric Alignment of Extreme Events

Authors:
Jokubas Petkevicius↗

arXiv:2606.25810v1 Announce Type: new Abstract: Let Q_n = B_n + J_n be the quadratic covariation matrix of a high-dimensional semimartingale, where J_n is the jump component and B_n is the diffusion component. We prove that spectral collapse occurs – meaning the ratio of the leading eigenvalue to the trace converges to 1 and the effective rank converges to 1 – if and only if the jump directions are geometrically aligned in a weighted sense and the background diffusion is asymptotically negligible. The proof separates into two steps: geometric alignment of jump directions forces spectral concentration of J_n; background negligibility then propagates this to the full system. We extend to the stochastic setting and prove convergence in probability under natural conditions on the jump process. The framework gives a scalar diagnostic for detecting when a high-dimensional system is dominated by extreme events.

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06.
arXiv (CS.AI) 2026-06-18

From Specification to Execution: AI Assisted Scientific Workflow Management

Authors:
Komal Thareja↗Hamza Safri↗Rajiv Mayani↗Anirban Mandal↗Ewa Deelman↗

arXiv:2606.18425v1 Announce Type: cross Abstract: Scientific workflow management systems (WMS) support scalable and reproducible execution of complex pipelines, but workflow design, implementation, and debugging remain largely manual and require significant expertise. Recent approaches using large language models (LLMs) show promise for workflow generation from natural language, but often rely on direct code synthesis, which limits transparency, reproducibility, and integration with workflow systems. We present an AI-assisted approach to scientific workflow management that combines specification-driven workflow generation, automated debugging, and distributed execution. The method introduces a structured specification phase that separates workflow intent, design, and implementation, allowing validation prior to code generation. We also develop an LLM-based debugging agent that diagnoses and resolves failures across multiple system layers. To support distributed execution and user interaction, we integrate Pegasus, a widely used WMS, with a Model Context Protocol (MCP) layer, providing a unified interface for workflow submission, monitoring, and control. We evaluate the approach using a federated learning workflow for medical imaging, chosen for its parallel, iterative, and dependency-intensive structure. The system generated and executed large-scale workflows with thousands of jobs, reduced debugging effort, and allowed non-expert users to construct workflows with expert-level design patterns. These results indicate that end-to-end AI-assisted workflow generation and execution is feasible, and point toward AI-driven platforms for managing the scientific workflow lifecycle.

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07.
arXiv (CS.CV) 2026-06-15

A Multi-Domain Feature Fusion Framework for Generalizable Deepfake Detection Across Different Generators

Authors:
Amna Amjid↗Sana Qadir↗Mehwish Fatima↗Raja Khurram Shahzad↗

Deepfakes are artificially generated images, audio, or videos that threaten privacy, security, and information integrity. Detecting such content is crucial for countering disinformation, as the latest models generate highly realistic content. While spatial- or frequency-based approaches achieve good detection rates on Generative Adversarial Networks (GANs)-based generated deepfakes, they often struggle with recent diffusion model-generated images. In particular, existing approaches rarely exploit complementary multi-domain representations or systematically evaluate cross-generator robustness. To address these challenges, we propose a multi-domain deepfake detection framework called SGFF-Net (Spatial-Gradient-Frequency Fusion Network) that integrates spatial, gradient, and DWT (Discrete Wavelet Transform)-based frequency representations within a dual residual learning architecture. Experimental results show that the SGFF-Net achieves 98.95\% accuracy in intra-dataset evaluation and improves performance in both cross-model (70.46\%) and cross-paradigm (69.94\%) settings. Incorporating multi-source training and data augmentation further enhances robustness, increasing accuracy from 70.46\% to 79.80\% in cross-model evaluation, from 69\% to 78\% in cross-paradigm evaluation, and from 61.50\% to 75.80\% on real-world data. Unlike single-domain detectors, the SGFF-Net learns complementary forensic cues across spatial, gradient, and wavelet-frequency domains, resulting in greater robustness under cross-generator and cross-paradigm evaluation. The results further show that combining multi-domain representations with data diversity and augmentation substantially improves generalization, providing practical insights for developing more reliable deepfake detection systems.

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08.
arXiv (CS.AI) 2026-06-12

Structured vs. Unstructured Pruning: An Exponential Gap

Authors:
Davide Ferre'↗Fr\'ed\'eric Giroire↗Frederik Mallmann-Trenn↗Emanuele Natale↗

arXiv:2603.02234v3 Announce Type: replace-cross Abstract: The Strong Lottery Ticket Hypothesis (SLTH) states that large, randomly initialized neural networks contain sparse subnetworks capable of approximating a target function at initialization without training, suggesting that pruning alone is sufficient. Pruning methods are typically classified as unstructured, where individual weights can be removed from the network, and structured, where parameters are removed according to specific patterns, as in neuron pruning. Existing theoretical results supporting the SLTH rely almost exclusively on unstructured pruning, showing that logarithmic overparameterization suffices to approximate simple target networks. In contrast, neuron pruning has received limited theoretical attention, despite its practical appeal for direct hardware speedups. In this work, we consider the problem of approximating a single bias-free ReLU neuron by pruning hidden units of a randomly initialized two-layer ReLU network, effectively isolating the intrinsic limitations of neuron pruning. We show that achieving an $\varepsilon$-approximation requires a starting network size of $\Omega(1/\varepsilon)$ for neuron pruning, whereas weight pruning succeeds with only $O(\log(1/\varepsilon))$ hidden units, revealing an exponential separation between the two approaches.

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09.
arXiv (CS.AI) 2026-06-18

Essential Subspace Merging for Multi-Task Learning

Authors:
Longhua Li↗Lei Qi↗Xin Geng↗Qi Tian↗

arXiv:2606.19164v1 Announce Type: cross Abstract: Model merging aims to enable multi-task learning by integrating the capabilities of multiple models fine-tuned from the same pre-trained checkpoint into a single model. Its core challenge is inter-task interference among task-specific parameter updates. In this paper, we analyze the output shifts induced by task updates and observe that their energy is concentrated in a small number of principal directions. We call the subspace spanned by these directions the essential subspace. In contrast, most remaining directions carry little task-relevant energy, but their accumulation across multiple task updates can cause severe interference during merging. Motivated by this observation, we propose Essential Subspace Decomposition (ESD), which decomposes each task update according to the principal components of its activation shift. Based on ESD, we introduce Essential Subspace Merging (ESM), a training-free static merging method that orthogonalizes and fuses essential components into one compact multi-task model. We further extend ESM to ESM++, a training-free dynamic merging method that decomposes task-specific residuals into low-rank experts and selects the most relevant expert through prototype-based routing during forward inference. Extensive experiments across multiple task sets and model scales demonstrate that ESM and ESM++ effectively preserves task knowledge while reducing inter-task interference.

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10.
arXiv (CS.AI) 2026-06-24

Average Rankings Mask Per-Subject Optimality: A Friedman-Nemenyi Benchmark of EEG Motor-Imagery BCI Decoders

Authors:
Xavier Vasques↗Paul Barbaste↗Olivier Oullier↗

arXiv:2606.24394v1 Announce Type: cross Abstract: Electroencephalography (EEG) is the dominant non-invasive modality for brain-computer interfaces (BCIs), yet reliable decoding of motor imagery is hampered by inter- and intra-individual variability. A recurring claim is that one decoding pipeline, most often a spatial or Riemannian method, is broadly preferable. We test the weakest version of that claim under the most favourable conditions. Using the Mother of All BCI Benchmarks (MOABB) framework, we evaluated 1,056 decoding configurations (feature extractor x scaler x classifier), >340,000 subject-level model fits, across three public left-versus-right motor-imagery datasets (PhysionetMI, 109 participants; Cho2017, 52; Zhou2016, 4) and two frequency bands (8-15 Hz, 8-30 Hz). Every model is fit and tested within a single session of a single participant, the easiest regime, giving every pipeline its best chance. We apply the statistics standard for multi-classifier comparison: Friedman omnibus tests, Nemenyi critical-difference analysis and Wilcoxon signed-rank tests with effect sizes. Covariance tangent-space projection (cov-tgsp) and Common Spatial Patterns (CSP) are the strongest families, but their ordering is dataset-dependent and, on the largest and most heterogeneous cohort (PhysionetMI), statistically indistinguishable (Nemenyi p = 0.27; Kendall's W = 0.11). At the individual level the single best pipeline is optimal for only 35% of PhysionetMI participants, and nonlinear descriptors are best for roughly one third; matching pipeline to participant adds about seven accuracy points over the best fixed choice. The ranking is not an artefact of dimensionality, and classifier and scaler choices are secondary to the feature representation. Even in the easiest regime, no single pipeline dominates: a lower bound on the personalization problem and a quantitative case for participant-aware model selection rather than a universal decoder.

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11.
medRxiv (Medicine) 2026-06-24

Uncovering the fitness of endemically circulating Zika virus strains

Authors:
Chen↗Fritz↗Clapham↗H. E↗Lefrancq↗Salje↗BUZZ study team↗

Zika virus (ZIKV) is an arbovirus that usually causes few symptoms and has circulated endemically in Asia for decades. However, a large outbreak in South America in 2015 uncovered the serious risk of congenital Zika syndrome in infants born from ZIKV infected mothers. It is unknown whether a lineage with distinct pre-existing fitness advantage emerged from Asia to cause the South American outbreak, and whether there is ongoing evolution that can result in future globally fit strains. Here we used 107 sequences from a single setting (Thailand) collected over an 18 year period (2006-2023). We used novel analytical tools to identify distinct lineages that have circulated in the population and estimated their relative epidemiological fitness. We found there have been six lineages circulating sequentially in the country, with regular emergence and replacement of lineages showing higher fitness than their predecessors. We identified 15 lineage-defining amino acid changes, including four well-documented fitness-enhancing mutations, and two UTR substitutions. The lineage that emerged in South America was evolutionarily linked to the highest-fitness lineage in Thailand, carrying seven of our lineage-defining substitutions acquired during endemic circulation there, and subsequently accumulating four additional changes. After the global pandemic, endemic ZIKV in Thailand continued to evolve, with newly emerged lineages showing novel mutations and increased fitness. Our findings have key implications for the monitoring of ZIKV and can help identify the pathway to increased transmissibility of this globally important pathogen.

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12.
arXiv (CS.AI) 2026-06-18

TRAP: Benchmark for Task-completion and Resistance to Active Privacy-extraction

Authors:
Moon Ye-Bin↗Nam Hyeon-Woo↗Baek Seong-Eun↗Yejin Yeo↗Tae-Hyun Oh↗

arXiv:2606.18996v1 Announce Type: cross Abstract: Agents are increasingly deployed in document-intensive workflows where sensitive private information is not an edge case but a routine input, e.g., an agent booking a flight needs passport numbers. In such settings, the agent must use private information to complete tasks accurately while never exposing it in its responses, because it cannot verify who is actually at the keyboard. These two obligations are in fundamental tension. A model capable enough to use private information for task completion can, by the same capability, be induced to reveal it. To evaluate the trade-off of task accuracy and privacy leakage, we introduce Task-completion and Resistance to Active Privacy-extraction (TRAP). Each scenario includes a document containing private information, a task query that requires the agent to invoke the correct tool using private fields, and an attack query that attempts to elicit the same information in natural language. Evaluating 22 models spanning frontier proprietary and open-source models at multiple scales, we find that all model families exhibit non-trivial leakage, and that instruction-following ability correlates with leakage rate. Existing prompt-based defenses reduce leakage but at significant cost to task accuracy. Prompt optimization fails to escape this trade-off. We demonstrate that this failure is not incidental. For any softmax-based model, no soft-constraint defense, e.g., prompt-based defenses, can jointly achieve high task success with zero leakage probability. Motivated by this impossibility result, we propose structural private field isolation, which replaces private fields with hash keys before they reach the model. This approach largely prevents leakage while keeping task accuracy.

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13.
arXiv (quant-ph) 2026-06-12

Multi-entropy in heavy local quenches

Authors:
Kosei Fujiki↗Kenya Tasuki↗

arXiv:2606.12526v1 Announce Type: cross Abstract: We study the time evolution of tripartite entanglement in heavy local quenches in two-dimensional holographic conformal field theories. Our diagnostic is the genuine multi-entropy of adjacent intervals, computed from both bulk and boundary perspectives. A perturbative bulk analysis shows that the first-order small-mass perturbation around the vacuum geodesic network cancels identically at any time after the quench. In the fully back-reacted geometry, a vacuum-subtracted genuine multi-entropy arises from a mismatch between the winding selected by the trivalent geodesic network and the windings selected independently by the pairwise geodesics. In the sharp quench limit, the time dependence of genuine multi-entropy is kinematically fixed to logarithms of rational functions of time and is independent of the heavy operator dimension. The CFT calculation reproduces the same formula within the heavy-light vacuum block approximation, where the branch choice in the heavy-background uniformization map corresponds to the winding selection in the bulk. These results indicate that, in this setup, the genuine multi-entropy is controlled by global saddle selection, rather than by a local energy response or quasiparticle propagation.

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14.
bioRxiv (Bioinfo) 2026-06-19

Morpho-FM: spatial molecular reconstruction from routine H&E histology using transcriptomic foundation-model priors

Authors:
Huang↗J.-J↗Feng↗Qu↗L.-H↗Zheng↗L.-L↗

Routine haematoxylin and eosin (H&E) histology captures tissue architecture at clinical scale, but lacks a direct molecular readout of the transcriptional programmes that organise tumour epithelium, stroma, vasculature and immune compartments. Spatial transcriptomics provides this context, yet cost, workflow complexity and sparse sampling limit routine use. Most existing histology-to-expression models are trained de novo on small paired cohorts and therefore remain weakly constrained when extrapolating from sparse measurements to dense, tissue-wide molecular maps. Here we introduce Morpho-FM, a weakly supervised framework that predicts spatial gene expression from routine H&E whole-slide images by conditioning a pretrained single-cell transcriptomic foundation-model prior on local histological neighbourhoods. A lightweight morphology-to-transcriptome adapter maps cached whole-slide histology features into a transcriptomic decoder, enabling prediction at measured locations, dense full-section reconstruction, and re-aggregation to the original measurement support. Across harmonized prostate cancer benchmarks, Morpho-FM achieved the strongest overall performance among five representative methods, reaching mean per-gene Pearson correlations of 0.286 in rotating single-slide evaluation and 0.298 in multi-slide held-out validation. The framework reproduced this advantage across kidney cancer sections, achieved a mean correlation of 0.210 across 56 directed single-slide evaluations and retained measurable predictive signal after external transfer to clear-cell renal cell carcinoma sections. Controlled ablation analyses identified pretrained transcriptomic initialization as a reproducible source of performance gain exceeding that attributable to changes in the histology feature backbone. Beyond predictive accuracy benchmarks, Morpho-FM recovered ERBB2-enriched tumour compartments, boundary-associated molecular gradients, and annotation-aligned tissue domains across Xenium and HER2ST breast cancer datasets. Together, these results support transcriptomic foundation-model priors as an effective constraint for morphology-conditioned molecular decoding and demonstrate the potential of Morpho-FM to extend spatial transcriptomic insight across routine pathology sections.

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15.
arXiv (CS.CL) 2026-06-16

Nemotron 3 Ultra: Open, Efficient Mixture-of-Experts Hybrid Mamba-Transformer Model for Agentic Reasoning

Authors:
NVIDIA↗Aaron Blakeman↗Aaron Thomas↗Aastha Jhunjhunwala↗Abhibha Gupta↗Abhinav Khattar↗Adam Rajfer↗Adi Renduchintala↗Adil Asif↗Aditya Vavre↗Adriana Flores Miranda↗Ahmad Bilal↗…

We introduce Nemotron 3 Ultra, a 550 billion total and 55 billion active parameter Mixture-of-Experts Hybrid Mamba-Attention language model. We pre-trained Nemotron 3 Ultra on 20 trillion text tokens, then extended the context length to 1M tokens, and post-trained using Supervised Fine Tuning (SFT), Reinforcement Learning (RL), and Multi-teacher On-Policy Distillation (MOPD). Nemotron 3 Ultra is our most capable model yet, employing multiple key technologies - LatentMoE, Multi Token Prediction (MTP), NVFP4 pre-training, multi-environment RLVR, MOPD, and reasoning budget control. Nemotron 3 Ultra achieves up to ~6x higher inference throughput as compared to state-of-the-art publicly available LLMs while attaining on-par accuracy. The state-of-the-art accuracy, high inference throughput, and 1M token context length make Nemotron 3 Ultra ideal for long-running autonomous agentic tasks. We open-source the base, post-trained, and quantized checkpoints, along with the training data and recipe on HuggingFace.

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16.
medRxiv (Medicine) 2026-06-24

Development and Validation of Machine Learning Models for Predicting Initiation of Emergency Dialysis in Advanced Chronic Kidney Disease

Authors:
Hirano↗Seki↗Watanabe↗Kubota↗Kawazoe↗

Background: Initiation of emergency dialysis, often requiring temporary catheter owing to unprepared definitive vascular access, is associated with infectious and vascular complications and suggests advanced chronic kidney disease (CKD) care gaps. Previous studies focused on kidney failure or dialysis timing. This study aimed to predict initiation of emergency dialysis using machine learning and baseline data. Methods: This retrospective cohort study used the Japan Medical Data Center claims data (2014-2022). Adults with an estimated glomerular filtration rate (eGFR)

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17.
arXiv (CS.CL) 2026-06-12

LLM-based Embeddings: Attention Values Encode Sentence Semantics Better Than Hidden States

Authors:
Yeqin Zhang↗Yunfei Wang↗Jiaxuan Chen↗Ke Qin↗Yizheng Zhao↗Cam-Tu Nguyen↗

Sentence representations are foundational to many Natural Language Processing (NLP) applications. While recent methods leverage Large Language Models (LLMs) to derive sentence representations, most rely on final-layer hidden states, which are optimized for next-token prediction and thus often fail to capture global, sentence-level semantics. This paper introduces a novel perspective, demonstrating that attention value vectors capture sentence semantics more effectively than hidden states. We propose Value Aggregation (VA), a simple method that pools token values across multiple layers and token indices. In a training-free setting, VA outperforms other LLM-based embeddings, even matches or surpasses the ensemble-based MetaEOL. Furthermore, we demonstrate that when paired with suitable prompts, the layer attention outputs can be interpreted as aligned weighted value vectors. Specifically, the attention scores of the last token function as the weights, while the output projection matrix ($W_O$) aligns these weighted value vectors with the common space of the LLM residual stream. This refined method, termed Aligned Weighted VA (AlignedWVA), achieves state-of-the-art performance among training-free LLM-based embeddings, outperforming the high-cost MetaEOL by a substantial margin. Finally, we highlight the potential of obtaining strong LLM embedding models through fine-tuning Value Aggregation.

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18.
arXiv (CS.AI) 2026-06-24

AI-Driven Predictive Maintenance with Environmental Context Integration for Connected Vehicles: Simulation, Benchmarking, and Field Validation

Authors:
Kushal Khemani↗Anjum Nazir Qureshi↗

arXiv:2603.13343v3 Announce Type: replace-cross Abstract: Predictive maintenance for connected vehicles offers the potential to reduce unexpected breakdowns and improve fleet reliability, but most existing systems rely exclusively on internal diagnostic signals and are validated on simulated or industrial benchmark data. This paper presents a contextual data fusion framework integrating vehicle-internal sensor streams with external environmental signals – road quality, weather, traffic density, and driver behaviour – acquired via V2X communication and third-party APIs, with inference at the vehicle edge. The framework is evaluated across four layers. A feature group ablation study on a physics-informed synthetic dataset shows contextual features contribute a 2.6-point F1 improvement; removing all context reduces macro F1 from 0.855 to 0.807. On the AI4I 2020 benchmark (10,000 samples), LightGBM achieves AUC-ROC 0.973 under 5-fold stratified cross-validation with SMOTE confined to training folds. A noise sensitivity analysis shows macro F1 remains above 0.88 at low noise and degrades to 0.74 at high noise. Most critically, the pipeline is validated on real-world telemetry from five vehicles across three countries (India, Germany, Brazil), comprising 992 trips and 11 evaluable service events identified from component wear resets in the trip logs. Across six wear-driven events spanning four vehicles, the model achieves 100% detection with mean MAE of 12.2 days. A fine-tuning ablation shows the base synthetic model already achieves 6/6 binary detection; per-vehicle adaptation reduces wear-driven MAE from 25.9 to 12.2 days. SHAP analysis confirms contextual and interaction features rank among the top 15 predictors. Edge-based inference reduces estimated latency from 3.5 seconds to under 1.0 second relative to cloud-only processing.

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19.
arXiv (CS.CV) 2026-06-18

DreamReg: Belief-Driven World Model for 2D-3D Ultrasound Registration

Authors:
Luoyao Kang↗Yuelin Zhang↗Jiwei Shan↗Haifan Gong↗Qingpeng Ding↗Shing Shin Cheng↗

Ultrasound (US) is widely used for surgical navigation, yet real-time registration between intraoperative 2D slices and preoperative 3D volumes remains challenging due to partial observability, speckle noise, and the action-dependent US acquisition. Existing methods are one-shot or short-horizon, making it hard for them to gather evidence over time or capture how surgeons adjust probe motion based on on-screen feedback. We propose DreamReg, a belief-driven world-model framework that formulates 2D-3D registration as belief updating over rigid transformations. DreamReg maintains a latent belief state that summarizes past observations and poses information, and continuously refines the transformation through learned dynamics as new slices arrive. During training, DreamReg is exposed to probe-motion trajectories that mimic clinical scanning behavior and learns to update its belief by conditioning pose refinement on the current US observation. During inference, DreamReg refines registration via internal imagination: it rolls out the learned world model to simulate candidate probe motions and their predicted observations, and integrates these imagined outcomes to converge to an accurate rigid transformation. Experiments on CAMUS and u-RegPro datasets demonstrate improved robustness and competitive registration accuracy for real-time guidance compared with state-of-the-art methods.

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20.
medRxiv (Medicine) 2026-06-24

Rare protein-coding variation and the genetic architecture of height in >1.4 million individuals

Authors:
Kosmicki↗J. A↗Ganel↗Watanabe↗Joseph↗Gaynor↗S. M↗Kessler↗M. D↗Backman↗J. D↗Mbatchou↗…

Highly heritable, polygenic, and easily measured, adult height has long been the model trait in human genetics. While the landscape of height-associated common genetic variation has been studied extensively, rare variation remains relatively unexplored. Using rare protein-altering variants in a discovery set of 826,066 exomes, we identify 207 height-associated genes - 98% of which replicate in an additional 624,567 individuals. The rarest and most deleterious class of variation, singleton (frequency

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21.
arXiv (math.PR) 2026-06-25

Face volume densities of positive-intensity and ideal Poisson–Voronoi tessellations in hyperbolic spaces

Authors:
Matteo D'Achille↗Christoph Th\"ale↗

arXiv:2606.26049v1 Announce Type: new Abstract: We determine analytically for all $k\in\{0,1,\ldots,d-1\}$ the $k$-volume densities of a Poisson–Voronoi tessellation of intensity $\lambda>0$ in the $d$-dimensional hyperbolic space of constant curvature $-1$. This largely extends previous results of Isokawa in dimensions two and three. As applications, we provide closed form expressions for all face volume densities and all typical face volumes of the ideal Poisson–Voronoi tessellation (IPVT), which is the low-intensity limit as $\lambda\downarrow0$ of the hyperbolic Poisson–Voronoi tessellation. As a main tool we develop a new Blaschke–Petkantschin–type formula in hyperbolic space.

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22.
Nature (Science) 2026-06-10

Amplified Arctic iceberg traffic reshapes benthic biodiversity

Authors:
Thomas Krumpen↗

The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs. At the same time, four decades of shipboard records show that the occurrence of icebergs increased abruptly in the early 2000s. Backtracking links these icebergs to the main outlet glaciers in northeast Greenland and the Russian High Arctic. In northeast Greenland, the timing of glacier destabilization coincides with this rise, whereas sparse satellite coverage in the Russian sector limits temporal attribution despite indications of enhanced glacier activity. A model sensitivity study shows that, apart from intensified calving, a more dynamic sea ice cover enhances downstream transport of glacial ice. Along these pathways, increased iceberg activity could reshape deep-sea habitats through enhanced melt and associated lithogenic input, and elevate navigational hazards as maritime traffic expands in the Arctic. Although modest compared with the iceberg discharges of Pleistocene Heinrich events, this mechanism provides a modern analogue of long-range cryospheric influence on the seafloor in a warming climate. Accelerated Arctic glacier disintegration and a more dynamic sea ice cover are increasing iceberg-delivered dropstones in the deep ocean, reshaping seafloor habitats and extending cryospheric impacts far beyond glaciers.

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23.
arXiv (CS.LG) 2026-06-16

A nonparametric two-sample test using a parametric integral probability metric

Authors:
Yuha Park↗Yongdai Kim↗

arXiv:2606.16941v1 Announce Type: cross Abstract: Detecting distributional differences between two independent samples is a fundamental problem in statistics and machine learning. Nonparametric two-sample testing provides a principled framework for determining whether two samples are drawn from the same underlying distribution, without assuming any specific parametric form for the distribution. In this study, we propose a new two-sample test statistic based on a newly introduced integral probability metric (IPM), using a specially designed parametric discriminator class with a single node of a neural network. We show that the resulting test statistic, called PReLU-IPM, is nonparametric and establish theoretical guarantees for the associated two-sample testing procedure, PReLU-TST, including its consistency and asymptotical equivalence to nonparametric IPM-based tests under regularity conditions. By analyzing multiple simulated and real benchmark datasets, we demonstrate that PReLU-TST achieves higher power across a range of alternatives or performs comparably to its competitors, for finite samples.

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24.
arXiv (quant-ph) 2026-06-15

Implementation of two-qubit Rydberg operations on neutral Rb-87 atoms in systems with different intermediate states

Authors:
I. V. Iukhnovets↗O. V. Bychkova↗I. B. Bobrov↗A. P. Gordeev↗M. Y. Goloshchapov↗G. I. Struchalin↗S. S. Straupe↗

arXiv:2606.13975v1 Announce Type: new Abstract: This work presents an experimental setup for implementing two-qubit operations on neutral atoms ($^{87}$Rb) with the possibility of using two different Rydberg excitation schemes. One of them uses 5P$_{1/2}$ as the intermediate level and applies the second-stage beam locally to the addressed atoms. The second scheme uses the 6P$_{3/2}$ level; in this scheme, the particles to be entangled are moved to a separate zone through which both Rydberg beams pass. The advantages and limitations of both schemes are analyzed. Based on numerical modeling performed with a Julia package developed by the authors, it is demonstrated that the spatial configuration has a greater effect on quantum-operation fidelity than the choice of intermediate level. An experimental implementation of the scheme using the 6P$_{3/2}$ level is demonstrated, making it possible to achieve a two-qubit operation fidelity of 94%.

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25.
arXiv (quant-ph) 2026-06-11

Optimizing Encoder Circuits of Entanglement-Assisted Quantum LDPC Codes via Beam Search

Authors:
Aditya Sodhani↗Pavan Kumar↗Shayan Srinivasa Garani↗Keshab K. Parhi↗

arXiv:2606.11468v1 Announce Type: new Abstract: Entanglement-assisted (EA) quantum QC-LDPC codes offer strong error-correction capabilities with structured parity-check matrices, but their practical use depends on efficient encoder circuits and the availability of pre-shared Bell pairs (ebits). In all encoder implementations based on the stabilizer formalism, the dominant contribution to this complexity comes from the use of controlled gates. In this paper, we adopt the Sharma-Kumar-Garani (SKG) encoder construction. We formulate the encoder optimization as a search over GF(2) row operations that decompose the binary matrix derived from its CNOT sub-sequence. We solve this problem using a beam search algorithm guided by a Hamming-distance heuristic. For the tested EA quantum QC-LDPC code families, the proposed method achieves CNOT-count reductions of 7.3-34.0% relative to the SKG baseline encoder. The optimized circuits also yield lower CNOT counts than Patel-Markov-Hayes synthesis on all tested instances and are verified by stabilizer-tableau simulation. These results show that substantial encoder simplification is possible for structured EA QC-LDPC codes.

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