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Authors: Pascal Geldsetzer ×

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Nature Medicine 2026-06-17 DOI: HASH:ccdda145cb3f3cb69cff4cc13eb57bb3

Why large-scale randomized trials of live-attenuated shingles vaccination for dementia prevention are urgently needed

Authors:

Pascal Geldsetzer ↗

In my view, we have never had as robust a body of evidence from observational data on an intervention for dementia as we do for live-attenuated shingles vaccination. Both a recent US National Institutes of Health expert workshop and an international expert consensus on Alzheimer’s disease drug repurposing identified large-scale randomized trials of shingles vaccination for dementia prevention as the crucial next step for the field.

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